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We analyze hundreds of thousands of used cars daily. 5L SUV FWD Hybrid. $46,993. We have 1,179 2022 Lexus RX 350 vehicles for sale that are reported accident free, 1,364 1-Owner cars, and 1,342 personal use cars. For Sale: 2022 Lexus RX 350L The average list price of a used 2022 Lexus RX 350 in Chicago, Illinois is $44,913. icvetzyniquwjahgpayywefsinkfcyqqknytslicolhcwjluvd